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You talk and the statement that the brain structure changes reminded me of Jiddu Krishnamurti. I quote him here:

" Insight is not a matter of memory, of knowledge and time, which are all thought. So I would say insight is the total absence of the whole movement of thought as time and remembrance. So there is direct perception. It is as though I have been going North for the last ten thousand years, and my brain is accustomed to going North, and somebody comes along and says, that will lead you nowhere, go East. When I turn round and go East the brain cells have changed. Because I have an insight that the North leads nowhere.
I will put it differently. The whole movement of thought, which is limited, is acting throughout the world now. It is the most important action, we are driven by thought. But thought will not solve any of our problems, except the technological ones. If I see that, I have stopped going North. I think that with the ending of a certain direction, the ending of a movement that has been going on for thousands of years, there is at that moment an insight that brings about a change, a mutation, in the brain cell."

Questioning Krishnamurti, p 165