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I thoroughly enjoyed the discussion with Paul Zak. A few questions came up which would be interesting to discuss further.

1) How does the trust response change with exposure to prolonged stress? I think about the millions of people who live on less than $2/day and wonder how their brain chemistry may or may not be modified by such prolonged exposure to stress.

2) I wonder how societies such as Rwanda or South Africa that have endured such horrific trauma come to develop such helpful mechanisms as the Truth and Reconciliation Commission?

3) He mentioned that those who struggle with social anxiety disorder are somehow unable to be affected by oxytocin. Given that the amygdala is central to our fear and anxiety response I wonder how oxytocin interacts with the amygdala.

Great show. Keep up the good work.